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| Career Strikeouts per 9IP Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Strikeouts per 9IP | IP | Years | Single Season Leaderboard |
| 1. | Donald Phillips | 9.79 | 1139.6 | 1952-1955 | |
| 2. | John Alton | 9.74 | 1040.0 | 1952-1955 | |
| 3. | Jason Williams | 8.99 | 1006.7 | 1952-1955 | |
| 4. | Dante Ruiz | 8.85 | 1195.3 | 1952-1955 | |
| 5. | Michael Knepper | 8.38 | 1246.3 | 1952-1955 | |
| 6. | Fabian Cordova | 8.27 | 1094.7 | 1952-1955 | |
| 7. | James Leggett | 7.88 | 917.7 | 1952-1955 | |
| 8. | Ruben Ibarra | 7.87 | 960.0 | 1952-1955 | |
| 9. | Francis Wachter | 7.86 | 1087.6 | 1952-1955 | |
| 10. | Billy Delucia | 7.78 | 1004.7 | 1952-1955 | |
| 11. | Cameron Hagans | 7.48 | 1086.0 | 1952-1955 | |
| 12. | Harry Frink | 7.33 | 1004.3 | 1952-1955 | |
| 13. | Carl Nicosia | 7.27 | 1061.3 | 1952-1955 | |
| 14. | Harry Robin | 7.26 | 1082.3 | 1952-1955 | |
| 15. | Alexander Lenihan | 7.17 | 975.3 | 1952-1955 | |
| 16. | Michael Sturges | 7.15 | 915.3 | 1952-1954 | |
| 17. | Walter Meas | 6.71 | 976.3 | 1952-1955 | |
| 18. | Bill Pelfrey | 6.38 | 934.7 | 1952-1955 | |
| 19. | Osvaldo Valtierra | 6.36 | 970.6 | 1952-1955 | |
| 20. | Robert Stadler | 6.11 | 1086.3 | 1952-1955 | |
| 21. | Antonio Padula | 6.04 | 967.3 | 1952-1955 | |
| 22. | Winfred Converse | 6.00 | 922.7 | 1952-1955 | |
| 23. | Clyde Pearson | 5.96 | 1053.0 | 1952-1955 | |
| 24. | Bruce Carlson | 5.87 | 1133.3 | 1952-1955 | |
| 25. | Gary Wadsworth | 5.30 | 934.7 | 1952-1955 | |
| 26. | Jack Hitchcock | 4.93 | 1015.0 | 1952-1955 | |
| 27. | Joshua Stephens | 4.90 | 1043.7 | 1952-1955 | |
| 28. | Richard Bush | 4.78 | 965.7 | 1952-1955 | |
| 29. | Gerald Adkisson | 4.76 | 1051.0 | 1952-1955 |
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